Go to The Journal of Clinical Investigation
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Journal stats
  • Publication ethics
  • Publication alerts by email
  • Transfers
  • Advertising
  • Job board
  • Contact
  • Physician-Scientist Development
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Immunology
    • Metabolism
    • Nephrology
    • Oncology
    • Pulmonology
    • All ...
  • Videos
  • Collections
    • In-Press Preview
    • Resource and Technical Advances
    • Clinical Research and Public Health
    • Research Letters
    • Editorials
    • Perspectives
    • Physician-Scientist Development
    • Reviews
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • In-Press Preview
  • Resource and Technical Advances
  • Clinical Research and Public Health
  • Research Letters
  • Editorials
  • Perspectives
  • Physician-Scientist Development
  • Reviews
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Journal stats
  • Publication ethics
  • Publication alerts by email
  • Transfers
  • Advertising
  • Job board
  • Contact

Research Letter

  • 37 Articles
  • 0 Posts
  • ← Previous
  • 1
  • 2
  • 3
  • 4
  • Next →
Characterizing enteric pathology in MPS IIIA mice suggests disease-specific vulnerability among lysosomal storage disorders
Ewa A. Ziółkowska, Letitia L. Williams, Elizabeth M. Eultgen, Grace R. Kick, Xukai Ding, Alexander Sorensen, Steven Q. Le, Balraj Doray, Patricia I. Dickson, Robert O. Heuckeroth, Jonathan D. Cooper
Ewa A. Ziółkowska, Letitia L. Williams, Elizabeth M. Eultgen, Grace R. Kick, Xukai Ding, Alexander Sorensen, Steven Q. Le, Balraj Doray, Patricia I. Dickson, Robert O. Heuckeroth, Jonathan D. Cooper
View: Text | PDF

Characterizing enteric pathology in MPS IIIA mice suggests disease-specific vulnerability among lysosomal storage disorders

  • Text
  • PDF
Abstract

Authors

Ewa A. Ziółkowska, Letitia L. Williams, Elizabeth M. Eultgen, Grace R. Kick, Xukai Ding, Alexander Sorensen, Steven Q. Le, Balraj Doray, Patricia I. Dickson, Robert O. Heuckeroth, Jonathan D. Cooper

×

Epigenomic profiling links IGF2 oveexpression to anthracycline resistance in colorectal cancer organoids
Tara L Hogenson, William Phillips, Merih D Toruner, Zachry S. Poshusta, Luciana Almada, Hao Xie, Ryan M. Carr, Jenny J. Li, David L. Marks, Renzo Vera, Erik Jessen, Michael Barrett, Joleen Hubbard, Travis E. Grotz, Martin E. Fernandez-Zapico
Tara L Hogenson, William Phillips, Merih D Toruner, Zachry S. Poshusta, Luciana Almada, Hao Xie, Ryan M. Carr, Jenny J. Li, David L. Marks, Renzo Vera, Erik Jessen, Michael Barrett, Joleen Hubbard, Travis E. Grotz, Martin E. Fernandez-Zapico
View: Text | PDF

Epigenomic profiling links IGF2 oveexpression to anthracycline resistance in colorectal cancer organoids

  • Text
  • PDF
Abstract

Authors

Tara L Hogenson, William Phillips, Merih D Toruner, Zachry S. Poshusta, Luciana Almada, Hao Xie, Ryan M. Carr, Jenny J. Li, David L. Marks, Renzo Vera, Erik Jessen, Michael Barrett, Joleen Hubbard, Travis E. Grotz, Martin E. Fernandez-Zapico

×

Inherited salt retention is associated with increased IL-17 responses and autoimmunity
Muhammad Atif Rauf, Sanskriti Agarwal, Rebecca R. Baker, Jennifer Steeden, Alfredo Petrosino, Maria Kiliaris, Robert Unwin, Keith Siew, Alan D. Salama, Rhys D.R. Evans
Muhammad Atif Rauf, Sanskriti Agarwal, Rebecca R. Baker, Jennifer Steeden, Alfredo Petrosino, Maria Kiliaris, Robert Unwin, Keith Siew, Alan D. Salama, Rhys D.R. Evans
View: Text | PDF

Inherited salt retention is associated with increased IL-17 responses and autoimmunity

  • Text
  • PDF
Abstract

Authors

Muhammad Atif Rauf, Sanskriti Agarwal, Rebecca R. Baker, Jennifer Steeden, Alfredo Petrosino, Maria Kiliaris, Robert Unwin, Keith Siew, Alan D. Salama, Rhys D.R. Evans

×

Growth of PIK3CA-driven cerebral cavernous malformations does not require microbiome stimulation
Lun Li, Rhonda Lightle, Bader Ali, Georgeio Sader, Robert Shenkar, Sean P. Polster, Douglas A. Marchuk, Jan-Karl Burkhardt, Issam A. Awad, Mark L. Kahn
Lun Li, Rhonda Lightle, Bader Ali, Georgeio Sader, Robert Shenkar, Sean P. Polster, Douglas A. Marchuk, Jan-Karl Burkhardt, Issam A. Awad, Mark L. Kahn
View: Text | PDF

Growth of PIK3CA-driven cerebral cavernous malformations does not require microbiome stimulation

  • Text
  • PDF
Abstract

Authors

Lun Li, Rhonda Lightle, Bader Ali, Georgeio Sader, Robert Shenkar, Sean P. Polster, Douglas A. Marchuk, Jan-Karl Burkhardt, Issam A. Awad, Mark L. Kahn

×

Matrikines dictate the amplitude of inflammation in smoke-related Streptococcus pneumoniae pulmonary infection
Sarah W. Robison, Jindong Li, Kristopher R. Genschmer, Liliana Viera, Jeremy B. Foote, Landon Wilson, W. Edward Swords, J. Edwin Blalock, Amit Gaggar, Xin Xu
Sarah W. Robison, Jindong Li, Kristopher R. Genschmer, Liliana Viera, Jeremy B. Foote, Landon Wilson, W. Edward Swords, J. Edwin Blalock, Amit Gaggar, Xin Xu
View: Text | PDF

Matrikines dictate the amplitude of inflammation in smoke-related Streptococcus pneumoniae pulmonary infection

  • Text
  • PDF
Abstract

Authors

Sarah W. Robison, Jindong Li, Kristopher R. Genschmer, Liliana Viera, Jeremy B. Foote, Landon Wilson, W. Edward Swords, J. Edwin Blalock, Amit Gaggar, Xin Xu

×

De novo VPS16 missense variant causes infantile-onset dystonia with defective autophagic flux
Enrique Gonzalez Saez-Diez, Xutong Xue, Amy Tam, Hyo-Min Kim, Siofra Carty, Joshua Rong, Monica Ferrer-Socorro, Kathryn Yang, Darius Ebrahimi-Fakhari
Enrique Gonzalez Saez-Diez, Xutong Xue, Amy Tam, Hyo-Min Kim, Siofra Carty, Joshua Rong, Monica Ferrer-Socorro, Kathryn Yang, Darius Ebrahimi-Fakhari
View: Text | PDF

De novo VPS16 missense variant causes infantile-onset dystonia with defective autophagic flux

  • Text
  • PDF
Abstract

Authors

Enrique Gonzalez Saez-Diez, Xutong Xue, Amy Tam, Hyo-Min Kim, Siofra Carty, Joshua Rong, Monica Ferrer-Socorro, Kathryn Yang, Darius Ebrahimi-Fakhari

×

Macrophage–fibroblast signaling networks identified by single-cell RNA sequencing in juvenile systemic sclerosis
Aneri Shethji, Theresa Hutchins, Anwesha Sanyal, Tianhao Liu, Wei Chen, Kathryn S. Torok
Aneri Shethji, Theresa Hutchins, Anwesha Sanyal, Tianhao Liu, Wei Chen, Kathryn S. Torok
View: Text | PDF

Macrophage–fibroblast signaling networks identified by single-cell RNA sequencing in juvenile systemic sclerosis

  • Text
  • PDF
Abstract

Authors

Aneri Shethji, Theresa Hutchins, Anwesha Sanyal, Tianhao Liu, Wei Chen, Kathryn S. Torok

×

IL1RAP-expressing myeloid-stromal networks represent a therapeutic vulnerability to improve chemoimmunotherapy sensitivity in pancreatic cancer
Erin M. Dickey, Harper M. Marsh, Camilla Rydberg-Millrud, Haleh Amirian, Karthik Rajkumar, Manan Patel, Andrew Adams, Anuroop Allena, Kevin Van der Jeught, Nipun Merchant, Peter J. Hosein, Anna Bianchi, David Liberg, Jashodeep Datta
Erin M. Dickey, Harper M. Marsh, Camilla Rydberg-Millrud, Haleh Amirian, Karthik Rajkumar, Manan Patel, Andrew Adams, Anuroop Allena, Kevin Van der Jeught, Nipun Merchant, Peter J. Hosein, Anna Bianchi, David Liberg, Jashodeep Datta
View: Text | PDF

IL1RAP-expressing myeloid-stromal networks represent a therapeutic vulnerability to improve chemoimmunotherapy sensitivity in pancreatic cancer

  • Text
  • PDF
Abstract

Authors

Erin M. Dickey, Harper M. Marsh, Camilla Rydberg-Millrud, Haleh Amirian, Karthik Rajkumar, Manan Patel, Andrew Adams, Anuroop Allena, Kevin Van der Jeught, Nipun Merchant, Peter J. Hosein, Anna Bianchi, David Liberg, Jashodeep Datta

×

Single-cell spatial profiling identifies a mucosal-like epithelial signature in Hidradenitis suppurativa tunnels
Peter Dimitrion, Jesse Veenstra, Deangelo Ferguson, Ping Wang, Jeffrey Cruz, Tasneem F. Mohammad, Ian Loveless, Aamir Siddiqui, Iltefat H. Hamzavi, Li Zhou, Indra Adrianto, Qing-Sheng Mi
Peter Dimitrion, Jesse Veenstra, Deangelo Ferguson, Ping Wang, Jeffrey Cruz, Tasneem F. Mohammad, Ian Loveless, Aamir Siddiqui, Iltefat H. Hamzavi, Li Zhou, Indra Adrianto, Qing-Sheng Mi
View: Text | PDF

Single-cell spatial profiling identifies a mucosal-like epithelial signature in Hidradenitis suppurativa tunnels

  • Text
  • PDF
Abstract

Authors

Peter Dimitrion, Jesse Veenstra, Deangelo Ferguson, Ping Wang, Jeffrey Cruz, Tasneem F. Mohammad, Ian Loveless, Aamir Siddiqui, Iltefat H. Hamzavi, Li Zhou, Indra Adrianto, Qing-Sheng Mi

×

Dynamic remodeling of portal vessels by Clec4g+ endothelial cells in liver growth and homeostasis
Sarah Platt, Norhan B.B. Mohammed, Joseph Brancale, Caroline S.C. Tippett, Kevin Seo, Silvia Vilarinho
Sarah Platt, Norhan B.B. Mohammed, Joseph Brancale, Caroline S.C. Tippett, Kevin Seo, Silvia Vilarinho
View: Text | PDF

Dynamic remodeling of portal vessels by Clec4g+ endothelial cells in liver growth and homeostasis

  • Text
  • PDF
Abstract

Authors

Sarah Platt, Norhan B.B. Mohammed, Joseph Brancale, Caroline S.C. Tippett, Kevin Seo, Silvia Vilarinho

×
  • ← Previous
  • 1
  • 2
  • 3
  • 4
  • Next →

No posts were found with this tag.

Advertisement

Copyright © 2026 American Society for Clinical Investigation
ISSN 2379-3708

Sign up for email alerts