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Research LetterIn-Press PreviewCell biologyOncology Open Access | 10.1172/jci.insight.209426

ROCK2 inhibitor belumosudil overcomes resistance to KRAS inhibition in pancreatic cancer models

Alejandra M. Marinelarena,1 Thao D. Pham,1 Jeffrey H. Becker,1 Apurba Majumder,1 and Hidayatullah G. Munshi1

1Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, United States of America

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1Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, United States of America

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1Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, United States of America

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1Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, United States of America

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1Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, United States of America

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Published November 3, 2026 - More info

JCI Insight. https://doi.org/10.1172/jci.insight.209426.
Copyright © 2026, Marinelarena et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Published November 3, 2026 - Version history
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