IL-6 serum levels are elevated in Parkinson's disease patients with fatigue compared to patients without fatigue
JR Pereira, LV Dos Santos, RMS Santos… - Journal of the …, 2016 - Elsevier
To investigate the influence of interleukin-6 (IL-6) and soluble tumor necrosis factor
receptors (sTNFR) in fatigued Parkinson's disease (PD) patients. Forty-four PD patients were
evaluated, and fatigue was assessed with the Parkinson Fatigue Scale. Logistic regression
analysis was used to evaluate the contribution of disease severity scores and cytokine levels
on fatigue scores. A receiver operating characteristic (ROC) curve was used to evaluate the
diagnostic values of IL-6 in fatigue. Fatigued PD patients had worse cognitive function and …
receptors (sTNFR) in fatigued Parkinson's disease (PD) patients. Forty-four PD patients were
evaluated, and fatigue was assessed with the Parkinson Fatigue Scale. Logistic regression
analysis was used to evaluate the contribution of disease severity scores and cytokine levels
on fatigue scores. A receiver operating characteristic (ROC) curve was used to evaluate the
diagnostic values of IL-6 in fatigue. Fatigued PD patients had worse cognitive function and …
