Non‐steroidal anti‐inflammatory drugs for acute gout

CMPG van Durme, MD Wechalekar… - Cochrane Database …, 2014 - cochranelibrary.com
CMPG van Durme, MD Wechalekar, R Buchbinder, N Schlesinger, D van der Heijde…
Cochrane Database of Systematic Reviews, 2014cochranelibrary.com
Background Gout is an inflammatory arthritis that is characterised by the deposition of
monosodium urate crystals in synovial fluid and other tissues. The natural history of articular
gout is generally characterised by three periods: asymptomatic hyperuricaemia, episodes of
acute gout and chronic gouty arthritis. Non‐steroidal anti‐inflammatory drugs (NSAIDs)
including selective cyclo‐oxygenase‐2 (COX‐2) inhibitors (COXIBs) are commonly used to
treat acute gout. Published guidelines recommend their use to treat acute attacks, using …
Background
Gout is an inflammatory arthritis that is characterised by the deposition of monosodium urate crystals in synovial fluid and other tissues. The natural history of articular gout is generally characterised by three periods: asymptomatic hyperuricaemia, episodes of acute gout and chronic gouty arthritis. Non‐steroidal anti‐inflammatory drugs (NSAIDs) including selective cyclo‐oxygenase‐2 (COX‐2) inhibitors (COXIBs) are commonly used to treat acute gout. Published guidelines recommend their use to treat acute attacks, using maximum recommended doses for a short time.
Objectives
cochranelibrary.com