Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice
J. Clin. Invest. Hong Lu, et al. 118:984 doi:10.1172/JCI32970 [
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Figure 2Renin inhibition dose-dependently decreased angiotensin peptide concentrations in mouse plasma. Angiotensin peptides in mouse plasma were resolved by HPLC and quantified with radioimmunoassay (
n = 4 per group). Data are mean ± SEM. *
P < 0.05 versus vehicle;
#P < 0.05 versus 2.5 mg/kg/d aliskiren.
