Noninvasive diagnosis of ruptured peripheral atherosclerotic lesions and myocardial infarction by antibody profiling
J. Clin. Invest. Kitty B.J.M. Cleutjens, et al. 118:2979 doi:10.1172/JCI32767 [
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Figure 2Detailed serological analysis of antigens E1 and E12. Antibody profile of clone E1 (
A,
E, and
H) and clone E12 (
B and
F); sensitivity and specificity of clones E1, E12, and E1 and E12 combined (
C,
D, and
G); and correlation of the response to clones E1 and E12 (
D) and E1 and TnT levels (
H) in patients with peripheral vascular disease (
A–
D) and coronary artery disease (
E–
H). Reactivity is represented as the ratio of OD
450 sample/(mean OD
450 + 3SD) for empty phage. (
A,
B,
E, and
F) Data points and horizontal bars represent reactivity of individual sera and mean reactivity, respectively. *
P < 0.05; **
P < 0.01; ***
P < 0.0001.